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Synthesis of α-fetoprotein and albumin by human embryonic hepatocytes

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Population aspects of the production of specific secreted proteins (serum albumin and α-fetoprotein) were studied in cultures of hepatocytes from human embryos at 6–12 weeks of development. A method based on local hemolysis in gel using sheep's erythrocytes conjugated with antibodies against the proteins for testing, was used. The overwhelming majority of hepatocytes were shownto synthesize both proteins.

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Éraizer, T.L., Él'gort, D.A. & Abelev, G.I. Synthesis of α-fetoprotein and albumin by human embryonic hepatocytes. Bull Exp Biol Med 83, 843–846 (1977). https://doi.org/10.1007/BF00798893

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  • DOI: https://doi.org/10.1007/BF00798893

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