Abstract
The abdominal aorta of rats was constricted between the orifices of the renal arteries. Renin activity was studied separately in the capillary part of the isolated glomeruli and in their arterioles. Renin activity was found in the capillary part of the glomeruli 3–4 weeks after the operation, and evidence of activation of the granular and agranular endoplasmic reticulum and Golgi complex was found in the mesangial cells. The results are interpreted as confirmation of the postulated reserve production of renin by the mesangial cells during a prolonged reduction in the renal circulation.
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Fedorov, V.I., Perov, Y.L. Reserve renin production by glomerular mesangial cells after experimental reduction of the renal circulation. Bull Exp Biol Med 83, 777–780 (1977). https://doi.org/10.1007/BF00798870
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DOI: https://doi.org/10.1007/BF00798870