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Characteristics of carcinogenesis in muscles with varying metabolism

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Two groups of cocks received the same dose of carcinogen (9,10-dimethyl-1,2-benzanthracene) into the thoracic (white) or femoral (red) muscles. Tumors (mostly rhabdomyosarcomas) occurred only in the thoracic muscles in periods of 2 to 5 months after the start of the experiment. Carbohydrate-phosphorus metabolism of this muscle is characterized by the prevalence of anaerobic glycolysis. The dynamics of morphological changes was studied at the site of carcinogen administration in the indicated two types of muscles during the pretumor period.

The muscle tissue reaction and protective-adaptive response to the carcinogen administration were different.

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Authors and Affiliations

  1. Laboratory of Pathomorphology of the Institute of Normal and Pathological Physiology, Akad. Med. Nauk SSSR, Moscow

    O. M. Pozdnyakov

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  1. O. M. Pozdnyakov
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Pozdnyakov, O.M. Characteristics of carcinogenesis in muscles with varying metabolism. Bull Exp Biol Med 55, 186–190 (1964). https://doi.org/10.1007/BF00798828

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  • DOI: https://doi.org/10.1007/BF00798828

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