Abstract
O-Benzyl-N-(benzyloxycarbonyl)-DL-serine methyl ester (1a) and peptides1 b–d with C-terminalO-benzylserine ester have been reduced with diisobutylaluminium hydride to yield the N-substituted aminoglyceraldehydes2 a–d. Using lithium tetrahydridoaluminate as the reducing agent the corresponding alcohols3 a–d have been obtained.
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Herrn Dr.Albert Groß (Fa. Kulzer) zum 60. Geburtstag gewidmet.
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Angrick, M. Notiz zur Darstellung vonN-substituierten Aminoglycerinaldehyden. Monatsh Chem 116, 645–649 (1985). https://doi.org/10.1007/BF00798790
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DOI: https://doi.org/10.1007/BF00798790