Abstract
An extract of cells of Ehrlich's ascites tumor inhibits the proliferative activity of its cells tissue specifically. The effect is expressed as a marked decrease in the number of dividing and DNA-synthesizing cells after injection of the extract. The mitotic index falls considerably as early as 2 h after the injection, reaches a minimum after 4–5 h, and returns to the control level again after 9–12 h. The radioactive index is on the whole uniformly low during the 18 h of the experiment.
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Antokhin, A.I., Barysheva, V.P., Romanov, Y.A. et al. Action of cell extract of Ehrlich's mouse ascites tumor on mitotic activity and DNA synthesis in that tumor. Bull Exp Biol Med 84, 1022–1025 (1977). https://doi.org/10.1007/BF00798536
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DOI: https://doi.org/10.1007/BF00798536