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Effect of cortisone-resistant thymocytes on endogenous colony formation in inbred mice

  • Microbiology and Immunology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Endogenous colonies were counted in the spleen of sublethally irradiated (CBAxC57BL/6)F1 hybrid mice after injection of thymocytes and lymph node cells treated with hydrocortisone and in intact CBA mice. Cortisone-resistance thymoctyes did not inhibit endogenous colony formation, whereas lymph node cells had a marked suppressive effect on endogenous colonies. In individual recipients the number of colonies in the spleen after injection of cortisone-resistant thymocytes was twice the number found in control irradiated hybrids.

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Semenkov, V.F., Kostyukov, A.A. Effect of cortisone-resistant thymocytes on endogenous colony formation in inbred mice. Bull Exp Biol Med 84, 997–999 (1977). https://doi.org/10.1007/BF00798528

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  • DOI: https://doi.org/10.1007/BF00798528

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