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Transport of chlorine ions in parietal cells of the gastric mucosa: Electron-histochemical and autoradiographic investigation

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The location of chlorine ions in the parietal cells of the mouse and rat gastric mucosa was studied by electron-histochemical and autoradiographic methods together with the direct method of detection of radioactive isotopes in tissue. On the basis of the results a scheme of specific transport of chlorine ions is proposed and envisages the transposition of individual layers of the cell membrane, double folds of the basal plasmalemma, tubulovesicles, and intracellular tubules. This interconversion takes place in the course of the secretory cycle of the cell and is directly dependent on it. A nonspecific pathway for the transport of the total chlorides of the gastric juice across intercellular spaces is postulated.

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Morozov, I.A. Transport of chlorine ions in parietal cells of the gastric mucosa: Electron-histochemical and autoradiographic investigation. Bull Exp Biol Med 84, 951–955 (1977). https://doi.org/10.1007/BF00798514

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  • DOI: https://doi.org/10.1007/BF00798514

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