Abstract
The location of chlorine ions in the parietal cells of the mouse and rat gastric mucosa was studied by electron-histochemical and autoradiographic methods together with the direct method of detection of radioactive isotopes in tissue. On the basis of the results a scheme of specific transport of chlorine ions is proposed and envisages the transposition of individual layers of the cell membrane, double folds of the basal plasmalemma, tubulovesicles, and intracellular tubules. This interconversion takes place in the course of the secretory cycle of the cell and is directly dependent on it. A nonspecific pathway for the transport of the total chlorides of the gastric juice across intercellular spaces is postulated.
Similar content being viewed by others
Literature Cited
I. A. Morozov, Arkh. Patol., No. 8, 78 (1971).
E. V. Kiseleva, A. G. Shilov, and N. B. Khristolyubova, Arkh. Anat., No. 12, 29 (1975).
A. A. Pokrovskii, M. M. Gapparov, and L. G. Levin, Fiziol. Zh. SSSR, No. 10, 1567 (1973).
A. A. Pokrovskii, M. M. Gapparov, L. G. Levin, et al.., Tsitologiya, No. 2, 175 (1975).
L. G. Caro and R. P. van Tubergen, J. Cell Biol.,15, 173 (1962).
I. Flexinos, M. Carballido, A. Louis, et al., Biol. Gastroent.,1, 57 (1971).
H. F. Helander and B. I. Hirschowitz Gastroenterology,67, 447 (1974).
H. Komnick, Protoplasma55, 414 (1962).
H. Komnick, M. Bierther, Histochemie,18, 337 (1969).
D. K. Normandin, Trans. Am. Microsc. Soc.,92, 381 (1973).
N. Pipan, Cytobiologie,8, 289 (1974).
A. van Harreveld and R. L. Potter, Stain Technol.,36, 185 (1961).
Rights and permissions
About this article
Cite this article
Morozov, I.A. Transport of chlorine ions in parietal cells of the gastric mucosa: Electron-histochemical and autoradiographic investigation. Bull Exp Biol Med 84, 951–955 (1977). https://doi.org/10.1007/BF00798514
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00798514