Abstract
The prothrombin time (PT) and the activated partial thromboplastin time (APTT) for untreated male Wistar rats were determined on the Sysmex CA-5000 Instrument for blood taken from the orbital sinus, tail vein, vena cava and aorta. Boxplot and statistical analysis was performed. Only orbital sinus puncture yields unpredictable and unacceptable variation/prolongation of clotting times.
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Salemink, P.J.M., Korsten, J. & de Leeuw, P. Prothrombin times and activated partial thromboplastin times in toxicology: a comparison of different blood withdrawal sites for wistar rats. Comp Haematol Int 4, 173–176 (1994). https://doi.org/10.1007/BF00798360
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DOI: https://doi.org/10.1007/BF00798360