Abstract
Sarcomas were induced in CBA/CBA-T6T6 mouse radiation chimeras by implantation of polyvinyl chloride film subcutaneously 13 months after irradiation and injection of donor's bone marrow. Of the 12 tumors studied 11 had the recipient's karyotype and one the donor's. The formation of connective-tissue cells from bone-marrow precursors thus, evidently, does not play an essential role in the histogenesis of sarcomas induced by plastics.
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Moizhess, T.G., Prigozhina, E.L. Histogenesis of mouse sarcomas induced by implantation of polyvinyl chloride film in radiation chimeras. Bull Exp Biol Med 81, 733–735 (1976). https://doi.org/10.1007/BF00797147
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DOI: https://doi.org/10.1007/BF00797147