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Effect of ethyrazole and parmidine on the development of experimental atherosclerosis in rabbits

  • Pharmacology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In rabbits receiving cholesterol with the diet for 3–4 months the accumulation of total cholesterol in the aorta and the degree of severity of atherosclerosis of the aorta were reduced by administration of ethyrazole and parmidine. These substances had no substantial effect on the blood cholesterol, triglyceride, and phospholipid levels of these animals.

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Literature Cited

  1. G. G. Avtandilov, The Dynamics of the Atherosclerotic Process in Man [in Russian], Moscow (1970).

  2. M. L. Belen'kii, Elements of Quantitative Evaluation of a Pharmacological Effect [in Russian], Leningrad (1963).

  3. E. R. Weibel, Morphometry of the Human Lung, Springer-Verlag (1963).

  4. V. E. Ryzhenkov, Farmakol. Toksikol., No. 1, 11 (1967).

    Google Scholar 

  5. É. M. Tarak and B. M. Ariél', Vestn. Akad. Med. Nauk SSSR, No. 7, 74 (1973).

    Google Scholar 

  6. G. H. Bragdon, in: Lipids and the Steroid Hormones in Clinical Medicine, Philadelphia (1960), p. 6.

  7. J. Damas and Y. Lallemand, C. R. Soc. Biol.,168, 379 (1974).

    Google Scholar 

  8. S. Gero and J. Srekeby, Cor. et Vasa (Prague),16, 233 (1974).

    Google Scholar 

  9. L. M. Morrison, G. S. Bajwa, et al., Atherosclerosis,16, 105 (1972).

    Google Scholar 

  10. B. P. Neri and C. S. Fringes, Clin. Chem.,19, 1201 (1973).

    Google Scholar 

  11. O. Rave, H. Wagner, U. Hrubesch, et al., Arzneimittel-Forsch.,24, 1779 (1974).

    Google Scholar 

  12. T. Shimamoto, Jap. Heart J.,13, 537 (1972).

    Google Scholar 

  13. D. B. Zilversmith, Stand. Meth. Clin. Chem.,2, 132 (1958).

    Google Scholar 

  14. N. Zöllner and K. Kirsch, Z. Ges. Exp. Med.,135, 545 (1962).

    Google Scholar 

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Ryzhenkov, V.E., Tararak, É.M., Khechinashvili, G.G. et al. Effect of ethyrazole and parmidine on the development of experimental atherosclerosis in rabbits. Bull Exp Biol Med 81, 697–698 (1976). https://doi.org/10.1007/BF00797134

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  • DOI: https://doi.org/10.1007/BF00797134

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