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Pediatric Cardiology

, Volume 16, Issue 2, pp 82–84 | Cite as

Ventricular fibrillation in two infants treated with amiodarone hydrochloride

  • A. Pohlgeers
  • J. Villafane
Case Reports

Abstract

Antiarrhythmic agents may induce ventricular arrhythmias. Whereas amiodarone is a reported cause of ventricular fibrillation in children, there are no reported cases in infants. We observed two patients with atrial flutter and congestive heart failure who were treated with amiodarone. Both had anatomic heart defects and had failed conventional therapy. Ventricular fibrillation occurred 3 and 12 days after the initial dose. Q-T interval, electrolytes, digoxin level, and amiodarone level (one patient) were normal. Amiodarone may provoke life-threatening ventricular tachyarrhythmias during the convalescent period. Consideration should be given to monitoring in a hospital setting for at least 2 weeks following initiation of amiodarone therapy.

Key Words

Amiodarone hydrochloride Ventricular fibrillation Atrial flutter Infants 

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Copyright information

© Springer-Verlag New York Inc. 1995

Authors and Affiliations

  • A. Pohlgeers
    • 1
  • J. Villafane
    • 1
  1. 1.Division of Pediatric CardiologyUniversity of Louisville School of MedicineLouisvilleUSA

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