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Nature of dividing cells in the regenerating liver of xenogeneic radiation chimeras

  • Experimental Genetics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Chromosome analysis of cells isolated from the regenerating liver of 14 xenogeneic mouserat radiochimeras showed that of 763 metaphases examined 95 were donor in origin. One of this latter group of metaphases was tetraploid. Most probably the cells of donor karyotype isolated from the liver of the radiation chimeras are Kupffer cells or cells from extramedullary foci of hematopoiesis. Polyploid cells of donor karyotype may belong to the megakaryocytic line of differentiation or may be polyploid cells of an inflammatory focus.

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Faktor, V.M., Chernyshova, É.V., Uryvaeva, I.V. et al. Nature of dividing cells in the regenerating liver of xenogeneic radiation chimeras. Bull Exp Biol Med 78, 1072–1074 (1974). https://doi.org/10.1007/BF00796672

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  • DOI: https://doi.org/10.1007/BF00796672

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