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Comparative morphometric study of the ultrastructure of fibroblasts and cells of experimental rat fibrosarcomas

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Details are given of a morphometric and electron-microscopic analysis of the mitochondrial, ergastoplasmic, and polysomal systems of the cells of experimental rat fibrosarcomas and normal rat fibroblasts at various levels of differentiation. Normal fibroblasts at different levels of differentiation are shown to differ in the ratio between extracellular and intracellular protein synthesis. No statistical differences were found in the level of organization of the mitochondrial system or of total protein synthesis. The ultrastructural organization of fibrosarcoma cells is indistinguishable in all morphometric parameters from that of embryonic cells; i. e., in the structure of the apparatus for protein synthesis fibrosarcoma cells are undifferentiated.

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Authors
  1. A. S. Yagubov
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  2. V. A. Kats
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Yagubov, A.S., Kats, V.A. Comparative morphometric study of the ultrastructure of fibroblasts and cells of experimental rat fibrosarcomas. Bull Exp Biol Med 78, 1051–1054 (1974). https://doi.org/10.1007/BF00796665

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  • DOI: https://doi.org/10.1007/BF00796665

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