Summary
The authors developed a method of obtaining blood (nonhemolyzed serum) from the caudal blood vessels of white mice in amounts sufficient for serological and immunological examinations. A glass bulb was connected to a suction motor to reduce the pressure. This method permits systematic and repeated blood drawing (3.1–3.9 ml of blood from 10 mice)-5 times at intervals of 2–5 days. Blood drawing performed by method does not affect the condition of the mice and permits them to be used for other investigations.
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Literature Cited
N.S. Grodko and F.A. Chertkova, Zhur. Mikrobiol., Épidemiol. i Immunobiol. No. 11, 114(1958).
V.L. Troitskii and N.I. Kovaleva, Zhur. Mikrobiol., Épidemiol. i Immunobiol. No. 5, 60 (1947).
J. Ipsen, J. Immunol.,70, 171(1953).
J. Ipsen, J. Immunol.70, 426(1953).
L.J. Reed and H. Muench, Am. J. Hyg.27 493(1938).
M.F.A. Woodruff, B. Forman, and K.B. Fraser, J. Immunol.67, 57(1951).
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Kovtunovich, L.G., Shablovskaya, E.A. A method of obtaining blood from white mice. Bull Exp Biol Med 50, 751–754 (1961). https://doi.org/10.1007/BF00796056
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DOI: https://doi.org/10.1007/BF00796056