Summary
Carbohydrate and lipid metabolism, as well as the activity of alkaline glycerophosphatase, cytochrome oxidase, succinic dehydrogenase, and succinic dehydrogenase, were studied histochemically in the liver and lungs of irradiated rabbits. The activity of succinic dehydrogenase and cytochrome oxidase drops considerably in animals with acute radiation, sickness, whereas the activity of alkaline glycerophosphatase is markedly elevated. In addition, a considerable increase of the neutral fat content in the liver, with accumulation of underoxidized products of its splitting in the lungs. The amount of phospholipids is usually markedly reduced in both organs. The amount of glycogen in the liver changes but little; only during the first hours after irradiation and in the, dead animals is a loss of the glycogen store in the liver noted.
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Ivanov, A.E., Kurshakova, N.N. Histochemical data concerning some metabolic disturbances in acute radiation sickness. Bull Exp Biol Med 50, 700–704 (1961). https://doi.org/10.1007/BF00796040
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DOI: https://doi.org/10.1007/BF00796040