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Describing the electrocardiographic changes in dogs with experimental atherosclerosis under conditions of long observation

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

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Summary

The author presents data concering the dynamics of the ECG changes occurring in dogs following an intravenous injection of adrenalin under conditions of experimental atherosclerosis. As a result of 2- and 3-year systematic investigations, it was established that the adrenalin test aids in detecting latent forms of disturbed physiological compensatory mechanism, even at the early stages in the development of experimental atherosclerosis. This was manifested in the ECG by various combinations of pathological rhythms of cardiac activity; the negative cardiac shifts were polymorphic, indicating pronounced functional instability of the cardiac conducting system. As noted, the disturbances of the main functions of the cardiac muscle observed in the adrenal tests are cyclic in character with periods of rise and fall in the negative shifts. This is associated with the varying course of morphological changes occurring in atherosclerosis.

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  1. Experimental Division of the Sverdlovsk Institute of Scientific Research in Health Resorts and Physiotherapy, Sverdlovsk, USSR

    S. I. Serov

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  1. S. I. Serov
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Serov, S.I. Describing the electrocardiographic changes in dogs with experimental atherosclerosis under conditions of long observation. Bull Exp Biol Med 50, 681–685 (1961). https://doi.org/10.1007/BF00796035

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  • DOI: https://doi.org/10.1007/BF00796035

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