Summary
Anomalous origin of the right subclavian artery (ARSA) from the aorta distal to the normally positioned left subclavian artery is a relatively frequent congenital anomaly in subjects with left aortic arch. The purpose of this study was to determine the relative frequency of associated cardiovascular anomalies in individuals with this anomaly. From the records of approximately 11,000 pathologic specimens in the Registry of Cardiovascular Disease of United Hospital (St. Paul, MN, USA), we found 128 (1.2%) with ARSA.
Of the 128 ARSA, 117 (2.9%) occurred among 4102 instances of congenital heart disease.
The 117 cases with congenital heart disease and ARSA were conotruncal anomalies in 38%, septal defects in 28%, obstructive anomalies of the left side of the heart in 21%, right heart anomalies in 5%, and miscellaneous conditions in the other 8%. Down syndrome existed in 14 (12%) of the 117 specimens with ARSA and some congenital cardiac anomaly; nine of the latter had an atrioventricular canal (AVC) malformation.
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References
Beabout JW, Stewart JR, Kincaid OW (1964) Aberrant right subclavian artery: dispute of commonly accepted concepts.Amer J Roentgenology 92:855–864
Becker AE, Becker MJ, Edwards JE (1971) Congenital anatomic potentials for subclavian steal.Chest 60:4–13
Blake HA, Manion WC (1962) Thoracic arterial arch anomalies.Circulation 26:251–265
Edwards JE (1948) Anomalies of the derivatives of the aortic arch system.Med Clin No Amer 32:925–949
Evans PR (1950) Cardiac anomalies in Mongolism.Br Heart J 12:258–262
Goldstein WB (1965) Aberrant right subclavian artery in Mongolism.Amer J Roentgenol 95:131–134
Lo RNS, Leung PM, Lau KC, Yeung CY (1989) Congenital cardiovascular malformations in Chinese children with Down's syndrome.Chin Med J 102:382–386
Marino B, Vairo U, Corno A, Nava S, Guccione P, Calabro R, Marcelletti C (1990) Atrioventricular canal in Down syndrome: prevalence of associated malformations compared with patients without Down syndrome.Amer J Dis Child 144:1120–1122
Molz G, Burri B (1978) Aberrant subclavian artery (arteria lusoria): sex differences in the prevalence of various forms of the malformation.Virch Arch Path Anat 380:303–315
Park SC, Mathews RA, Zuberbuhler JR, Rowe RD, Neches WH, Lenox CC (1977) Down syndrome with congenital heart malformation.Amer J Dis Child 131:29–33
Rathore MH, Sreenivasan VV (1989) Vertebral and right subclavian artery abnormalities in the Down syndrome.Amer J Cardiol 63:1528–1529
Rowe RD, Uchida IA (1961) Cardiac malformation in Mongolism: a prospective study of 184 Mongoloid children.Amer J Med 31:726–735
Salomonowitz E, Edwards JE, Hunter DW, Castaneda-Zuniga WR, Lund G, Cragg AH, Amplatz K (1984) The three types of aortic diverticula.Amer J Roentgenol 42:673–679
Steward JR, Kincaid OW, Edwards JE (1964)An atlas of vascular rings and related malformations of the aortic arch system. Charles C Thomas, Springfield, IL, pp 3–155
Winter FS (1954) Persistent left superior vena cava: survey of world literature and report of thirty additional cases.Angiology 5:90–132
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Zapata, H., Edwards, J.E. & Titus, J.L. Aberrant right subclavian artery with left aortic arch: Associated cardiac anomalies. Pediatr Cardiol 14, 159–161 (1993). https://doi.org/10.1007/BF00795645
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DOI: https://doi.org/10.1007/BF00795645