Summary
A study has been carried out on proteolytic activity in the tissues of an intact and deafferentiated lung in cats and dogs. A modification of Adams' and Tugan's method has been developed (applicable to Soviet-made photographic materials and in account with the characteristics of tissues with a relatively small content of proteolytic enzymes) for determining proteolytic activity with the aid of substrate films.
It has been shown that in the early days after the removal of cerebrospinal sensory ganglia, the proteolytic activity in the lung tissues is increased, but by the 7th–9th day it falls down to normal, whereupon a progressive decrease in the activity of proteases is observed.
A decrease in the activity of proteolytic enzymes in the tissues of a deafferentated lung is attributed to predominance of sclerotic processes in the later periods after an operation.
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Literature Cited
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C. W. M. Adams and N. A. Tugan, J. Histochem. Cytochem., Vol. 9 (1961), p. 469.
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Alekseeva, G.V. Comparative study of the proteolytic activity in the tissues of the intact and deafferentated lung. Bull Exp Biol Med 62, 1111–1113 (1966). https://doi.org/10.1007/BF00795451
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DOI: https://doi.org/10.1007/BF00795451