Mechanism of the influence of hexamethonium on some functions of the kidney before and after its denervation
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In dogs overloaded with water diuresis decreases after subcutaneous injection of hexamethonium (C6) prior to as well as after denervation of the kidney. Decrease of diuresis under the influence of C6 lasts longer and is more marked after renal denervation. Counts after endogenic creatinine titration showed, that under the influence of C6 the return absorption in the loops is increased. Analysis of data obtained suggests that C6 acts directly on some elements of the nephron.
KeywordsPublic Health Creatinine Subcutaneous Injection Renal Denervation Hexamethonium
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