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Pediatric Cardiology

, Volume 16, Issue 4, pp 186–189 | Cite as

Successful thrombolytic therapy using tissue-type plasminogen activator in Kawasaki disease

  • S. Tsubata
  • F. Ichida
  • Y. Hamamichi
  • A. Miyazaki
  • I. Hashimoto
  • T. Okada
Article

Abstract

Thrombolytic therapy using tissue-type plasminogen activator was performed in a 7-month-old boy with massive mural thrombi in large coronary aneurysms due to Kawasaki disease. Magnetic resonance imaging successfully demonstrated mural thrombi in both proximal and distal coronary aneurysms and their disappearance after thrombolytic therapy. We conclude that for preventing acute myocardial infarction and sudden death intravenous and intracoronary thrombolytic therapy with tissue-type plasminogen activator may help in infants and children with Kawasaki disease who have thrombi in coronary aneurysms.

Key words

Kawasaki disease Ischemic heart disease Tissue-type plasminogen activator Thrombolytic therapy 

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Copyright information

© Springer-Verlag New York Inc. 1995

Authors and Affiliations

  • S. Tsubata
    • 1
  • F. Ichida
    • 1
  • Y. Hamamichi
    • 1
  • A. Miyazaki
    • 1
  • I. Hashimoto
    • 1
  • T. Okada
    • 1
  1. 1.Department of PediatricsToyama Medical and Pharmaceutical UniversityToyama City, ToyamaJapan

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