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Bromine metabolism in the thyroid gland of guinea pigs during experimental hyperthyroidism and in rats fed on methylthiouracil

  • Biochemistry and Biophysics
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

A significant increase in the weight of the thyroid glands and of the bromine content was noted in experimental hyperthyroidism of ginea pigs. The relative quantity of the protein-combined bromine does not change. Preliminary administration of bromine greatly decreases the entrance of bromine into the protein fraction of the thyroid gland tissue.

The percentage of bromine in the protein fraction of the thyroid gland tissue is considerably diminished in rats fed methylthiouracil, whereas the total amount of bromine entering the thyroid gland of experimental animals rises.

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Authors and Affiliations

  1. Institute of Biological Physics, Academy of Sciences of the USSR, Moscow

    I. N. Verkhovskaia & L. M. Tsofina

Authors
  1. I. N. Verkhovskaia
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  2. L. M. Tsofina
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Verkhovskaia, I.N., Tsofina, L.M. Bromine metabolism in the thyroid gland of guinea pigs during experimental hyperthyroidism and in rats fed on methylthiouracil. Bull Exp Biol Med 46, 1481–1485 (1958). https://doi.org/10.1007/BF00793490

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  • DOI: https://doi.org/10.1007/BF00793490

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