Summary
In the process of appearance of poliomyelitis virus mutants under the action upon the viral RNA of increased temperature, nitrous acid or proflavine in conditions of light, apart from the alteration of number of biological signs, there occur changes of the antigenic marker, determining the intratype antigenic specificity.
The change of this sign was mostly observed in proflavine induced mutants.
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Gendon, Y.Z. Variability of the intratype antigen marker of strains of poliomyelitis. Bull Exp Biol Med 56, 1114–1116 (1963). https://doi.org/10.1007/BF00792989
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DOI: https://doi.org/10.1007/BF00792989