Experimental study of the new antituberculosis drug diambutol
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Studies in vitro of diambutol (ethambutol), a new antituberculosis preparation, and of its analogs and homologs demonstrated that only the L-isomer of diambutol possessed high antituberculosis activity against various strains ofMycobact. tuberculosis both sensitive and resistant to the action of antituberculosis preparations.
A study of diambutol (L-form) on a model of hematogenic tuberculosis of albino mice demonstrated its high chemotherapeutic activity. Chemotherapeutic trails of the preparation being continued on other species of animals; further studies in its pharmacological properties and its effect on the macroorganism are also being made.
KeywordsPublic Health Experimental Study Tuberculosis Pharmacological Property Ethambutol
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