Summary
This work deals with a method of determining the hyaluronidase activity of the urine, suggested by A. G. Ginetsinskii and associates, for determination of the stage of rheumatic fever.
Ten healthy individuals and 75 rheumatic fever patients were examined (28 — in the active stage, 14 — in the stage of decline and 33 during remission). In the healthy individuals a curve was obtained which coincided with that presented by A. G. Ginetsinskii. In the patients with rheumatism hyaluronidase activity of the urine in considerable diuresis was greater than in the same conditions in the healthy persons. In the patients a active stage of rheumatism and to a lesser degree in the stage of decline an abnormal relationship of the hyaluronidase activity of the urine to diuresis was noted.
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Literature Cited
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Tanyukhina, E.I. Investigation of hyaluronidase activity as a method of evaluation of activity of rheumatic fever. Bull Exp Biol Med 56, 1071–1073 (1963). https://doi.org/10.1007/BF00792976
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DOI: https://doi.org/10.1007/BF00792976