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The influence of ovarian hormones on growth of the epithelium of the mammary glands

  • Experimental Biology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The author studied the effect of ovarian hormones (folliculin and progesterone) on the mitotic activity of the terminal portions of the mammary glands in ovariectomized mice. He showed that the mitotic activity of the epithelium in the mammary glands increases from zero to 9.41 mitoses per 1000 cells after daily administration of folliculin in a dose of 25 I. U. to ovariectomized females. The maximal mitotic activity is noted after 8 folliculin injections. Following 10 folliculin injections the mitotic activity becomes reduced. In comparison with folliculin, progesterone provokes a lesser rise of mitotic activity.

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Authors and Affiliations

  1. Laboratory of Growth and Development of the Institute of Experimental Biology of the AMN SSSR, Moscow

    S. S. Laguchev

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  1. S. S. Laguchev
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Laguchev, S.S. The influence of ovarian hormones on growth of the epithelium of the mammary glands. Bull Exp Biol Med 48, 1544–1548 (1959). https://doi.org/10.1007/BF00792754

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  • DOI: https://doi.org/10.1007/BF00792754

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