Advertisement

Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 5, pp 1723–1726 | Cite as

Restorative processes in dog muscles after free auto-and homografting

  • N. N. Bosova
Experimental Biology
  • 13 Downloads

Abstract

Whole gastrocnemius muscles, denervated 1 month previously by division of the tibial nerve, were autografted and homografted in dogs. The transplanted muscles took at the site of grafting, but some of the transplanted material died and was resorbed; myoblasts were liberated from the viable part of the disintegrating material. As a result of further differentiation of myogenic elements in the autografts the blood supply and innervation were restored in good time and the muscle organ reconstructed. Its contractile activity also was restored. The homografts did not take permanently: The newly formed muscle died because of the incompatibility reaction. Preliminary denervation is thus an effective means of preparing muscle tissue for subsequent autografting.

Key words

Transplantation of muscles denervation of muscles gastrocnemius muscle 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    N. N. Bosova, Byull. Éksp. Biol. Med., No. 3, 88 (1962).Google Scholar
  2. 2.
    A. A. Engibaryan, Zh. Éksp. Klin. Med., No. 4, 31 (1973).Google Scholar
  3. 3.
    R. P. Zhenevskaya, Dokl. Akad. Nauk SSSR,96, 217 (1954).Google Scholar
  4. 4.
    Z. P. Ignat'eva, Arkh. Anat., No. 1, 31 (1961).Google Scholar
  5. 5.
    A. A. Nemilov, Fundamentals of the Theory and Practice of Tissue and Organ Transplantation [in Russian], Leningrad (1940).Google Scholar
  6. 6.
    S. N. Pravednikov, Nov. Khir. Arkh., No. 4 (226), 4 (1960).Google Scholar
  7. 7.
    A. N. Studitskii, Dokl. Akad. Nauk SSSR,82, 1017 (1952).Google Scholar
  8. 8.
    A. N. Studitskii and N. N. Bosova, Arkh. Anat., No. 12, 18 (1960).Google Scholar
  9. 9.
    A. N. Studitskii and Z. P. Ignat'eva, Regeneration of Muscles in Higher Mammals [in Russian], Moscow (1961).Google Scholar
  10. 10.
    A. N. Filatov et al., Transplantation and Replacement of Tissues and Organs [in Russian], Leningrad (1960).Google Scholar
  11. 11.
    N. N. Bosova, Musc. Dystrophy Abstr.,18, 129 (1974).Google Scholar
  12. 12.
    B. M. Carlson, Am. J. Anat.,128, 21 (1970).Google Scholar
  13. 13.
    R. S. Hikida and J. A. Lombardo, J. Cell Biol.,61, 414 (1974).Google Scholar
  14. 14.
    L. A. Peer, Transplantation of Tissues, Vol. 1, Williams and Wilkins, Baltimore (1955).Google Scholar
  15. 15.
    P. R. Roy, J. Exp. Med. Sci.,9, 78 (1966).Google Scholar
  16. 16.
    M. H. Snow, Anat. Rec.,176, 185 (1973).Google Scholar

Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • N. N. Bosova

There are no affiliations available

Personalised recommendations