Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 5, pp 1659–1661 | Cite as

Heterogeneous hemoglobin system of anemic rats

  • I. M. Shur'yan
  • N. F. Starodub
  • A. N. Gritsak
Biochemistry and Biophysics


The fractional composition of hemoglobin from the peripheral blood, spleen, and bone marrow of intact and anemic rats was studied by electrophoresis in polyacrylamide gel. Anemia was produced by injecting phenylhydrazine hydrochloride into the animals. The basic principles of formation of the heterogenous hemoglobin system, depending on the source from which it was obtained and on the state of the animals, were established. The possible causes of the observed reorganization of the fractional composition of hemoglobin and its biological significance are discussed.

Key words

Hemoglobin fractions anemia rat 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    V. P. Dudarev, in: Mountains and the Blood System (Symposium) [in Russian], Frunze (1971), p. 36.Google Scholar
  2. 2.
    V. P. Dudarev, in: Mountains and Health [in Russian], Kiev (1974), p. 113.Google Scholar
  3. 3.
    N. A. Plokhinskii, Biometrics [in Russian], Moscow (1970).Google Scholar
  4. 4.
    N. N. Sirotinin and V. G. Antonenko, in: The Regulation of Respiration under Normal and Pathological Conditions [in Russian], Kuibyshev (1968), p. 23.Google Scholar
  5. 5.
    N. F. Starodub, Biokhimiya, No. 4, 757 (1974).Google Scholar
  6. 6.
    N. F. Starodub (N. F. Starodub), Visn. Akad. Nauk Ukr. RSR, No. 12, 44 (1974).Google Scholar
  7. 7.
    N. F. Starodub, Radiobiologiya, No. 1, 27 (1975).Google Scholar
  8. 8.
    N. F. Starodub, Usp. Sovrem. Biol., No. 2 (1976).Google Scholar
  9. 9.
    M. F. Starodub, (N. F. Starodub) and I. A. Kriklivii (I. A. Kriklivyi), Dopov. Akad. Nauk Ukr. RSR, Ser. B, No. 2, 165 (1975).Google Scholar
  10. 10.
    N. F. Starodub, I. A. Kriklivyi, and G. M. Rekun, Usp. Sovrem. Biol., No. 6, 414 (1975).Google Scholar
  11. 11.
    M. F. Starodub (N. F. Starodub) and I. M. Shur'yan, Dopov. Akad. Nauk Ukr. RSR, Ser. B, No. 5, 454 (1973).Google Scholar
  12. 12.
    J. F. Bartles and T. A. Borgess, J. Clin. Invest.,47, 679 (1968).Google Scholar
  13. 13.
    T. H. J. Huisman, I. Brandt, and J. B. Wilson, J. Biol. Chem.,243, 3675 (1968).Google Scholar
  14. 14.
    H. Kitchen, J. W. Eaton, and W. J. Taylor, Am. J. Vet. Res.,29, 281 (1968).Google Scholar
  15. 15.
    L. K. Kraus, I. Luchi, and T. Kraus Ann. N. Y. Acad. Sci.,149, 423 (1968).Google Scholar
  16. 16.
    A. G. Mauk, H. T. Whelan, G. R. Putz, et al., Science,185, 447 (1974).Google Scholar
  17. 17.
    M. Schulman, J. Martinez-Medellin, and R. Sidloi, Biochem. Biophys. Res. Commun.,56, 220 (1974).Google Scholar
  18. 18.
    S. Stein, J. G. Gherian, and A. Mazur, J. Biol. Chem.,246, 5827 (1971).Google Scholar
  19. 19.
    A. S. Tavill, G. A. Vanderhoff, and I. M. London, J. Biol. Chem.,247, 326 (1972).Google Scholar
  20. 20.
    G. Van Vliet and T. H. J. Huisman, Biochem. J.,93, 401 (1964).Google Scholar

Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • I. M. Shur'yan
  • N. F. Starodub
  • A. N. Gritsak

There are no affiliations available

Personalised recommendations