Abstract
The effect of an increased gravitational field on activity of the hypothalamo-hypophyseo-adrenal system was studied in experiments on guinea pigs. A single exposure led to activation of this system; however, during repeated exposure to radial acceleration the animals ceased to respond by an increase in the blood corticosteroid level, evidently on account of adaptation of the central components of the system and not of exhaustion of the adrenal cortex.
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Ryzhenkov, V.E., Sapronov, N.S. Functional state of the hypothalamo-hypophyseo-adrenal system in guinea pigs exposed to radial acceleration. Bull Exp Biol Med 82, 1638–1640 (1976). https://doi.org/10.1007/BF00790370
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DOI: https://doi.org/10.1007/BF00790370