Abstract
From the age of 30 days male rats were overfed for a long time with an excess of fats or carbohydrates, leading to obesity. Overfeeding with carbohydrates caused a greater gain in body weight and a greater increase in the weight of the epididymal fat and in metabolism of the fat cells than overfeeding with fat, but it did not lower the lipolytic activity of the aortic wall. Prolonged overfeeding with fats greatly reduced the lipolytic activity of the aortic wall. The results thus showed that a predisposition of the aortic wall to atherogenesis does not correlate with gain in weight and depends on the character of feeding.
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Nasledova, I.D., Fashchevskaya, I.A., Khmel'nitskaya, T.O. et al. Effect of different types of overfeeding on state of the vascular wall in rats. Bull Exp Biol Med 82, 1616–1618 (1976). https://doi.org/10.1007/BF00790364
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DOI: https://doi.org/10.1007/BF00790364