Skip to main content
SpringerLink
Log in

Atherosclerosis induced in rabbits by prolonged electrical stimulation of the hypothalamus

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of prolonged electrical stimulation of emotiogenic zones of the hypothalamus in rabbits on their blood lipid level and the development of atherosclerosis was studied with the aid of a specially designed autonomous system. A negative emotional state observed during stimulation was accompanied by hyperlipemia and by the development of atherosclerosis in one third of uncastrated and two thirds of castrated animals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. I. Vainshtein, in: Structural, Functional, and Neurochemical Organization of the Emotions (All-Union Symposium) [in Russian], Leningrad (1971), pp. 126–130.

  2. N. A. dmitrieva and V. I. Morev, in: Mechanisms of Regulation of Physiological Activity under Pathological Conditions [in Russian], Baku (1970), pp. 325–326.

  3. T. N. Oniani, Zh. Vyssh. Nerv. Deyat., No. 2, 230 (1975).

    Google Scholar 

  4. N. A. Yudaev (editor), Modern Methods of Determination of Steroid Hormones in Biological Fluids [in Russian], Moscow (1968), pp. 50–54.

  5. G. S. Stepanov, Lab. Delo, No. 10, 594 (1965).

    Google Scholar 

  6. K. V. Sudakov, Pat. Fiziol., No. 1, 3 (1975).

    Google Scholar 

  7. P. S. Khomulo, Pat. Fiziol., No. 2, 3 (1968).

    Google Scholar 

  8. P. S. Khomulo, Kardiologiya, No. 5, 140 (1974).

    Google Scholar 

  9. P. S. Khomulo and I. P. Zharova, Byull. Éksp. Biol. Med., No. 7, 17 (1972).

    Google Scholar 

  10. P. S. Khomulo, N. A. Dmitrieva, A. S. Ignatenko et al., in: Current Problems in the Biochemistry and Clinical Management of Atherosclerosis (Proceedings of a Conference) [in Russian], Chita (1973), pp. 142–144.

  11. N. L. Yastrebtsova and L. V. Simutenko, Dokl. Akad. Nauk SSSR,201, 1001 (1971).

    Google Scholar 

  12. W. G. Duncombe, Clin. Chim. Acta,9, 122 (1964).

    Google Scholar 

  13. C. H. Fiske and J. Subbarow, J. Biol. Chem.,66, 375 (1925).

    Google Scholar 

  14. M. Friedman et al., Am. J. Physiol.,223, 473 (1972).

    Google Scholar 

  15. P. Stolz, G. Rost, and G. Honigman, Z. Med. Labortech.,9, 215 (1968).

    Google Scholar 

Download references

Authors
  1. P. S. Khomulo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. A. Dmitrieva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. I. Eliner
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Khomulo, P.S., Dmitrieva, N.A. & Eliner, G.I. Atherosclerosis induced in rabbits by prolonged electrical stimulation of the hypothalamus. Bull Exp Biol Med 82, 1612–1615 (1976). https://doi.org/10.1007/BF00790363

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00790363

Key words

Search

Navigation