Skip to main content
SpringerLink
Log in

Changes in the brain serotonin and noradrenalin level in albino rats during training with emotionally different reinforcement

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Changes in the brain serotonin (5-HT) and noradrenalin (NA) concentration in the brain of rats during training with emotionally positive (food) and negative (pain) reinforcement were compared. Training of the animals in both cases was accompanied by elevation of the biogenic amine level, but during emotionally positive reinforcement the increase was greater than with emotionally negative reinforcement. Training the animals with food reinforcement was accompanied by an increase in 5-HT predominantly in the cerebral cortex, evidently reflecting the active functioning of the serotoninergic system. After training in a defensive situation, increased activity of the noradrenergic system was observed. The character of the change in the brain biogenic amine level during training thus depends on the emotional quality of the reinforcement used.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. P. Anokhina and G. D. Zabrodin, in: Stress and Its Pathogenetic Mechanisms [in Russian], Kishinev (1973), pp. 11–13.

  2. E. A. Gromova, in: Memory and Trace Processes (Abstracts of Proceedings of the Second Conference on Problems in Memory and Trace Processes) [in Russian], Pushchino-on-Oka (1970), p. 46.

  3. E. A. Gromova, in: Memory and Trace Processes (Abstracts of Proceedings of the Third Conference on Problems in Memory and Trace Processes) [in Russian], Pushchino-on-Oka (1974), p. 111.

  4. E. A. Gromova, N. A. Zemtsova, M. B. Zykov, et al., in: Stress and Its Pathogenetic Mechanisms [in Russian], Kishinev (1973), p. 62.

  5. É. Sh. Matlina, A. M. Baru, and V. N. Vasil'ev, in: Progress in Science and Technology. Series: “Physiology of Man and Animals,” Vol. 15, Physiology of Emotions [in Russian], Moscow (1975), p. 30.

  6. N. B. Essman, in: Biology of Memory (Symposium), Budapest (1971), pp. 213–238.

  7. E. A. Gromova, in: Second International Congress of CIANS, Abstract, Prague (1975), p. 135.

  8. T. P. Semyonova (T. P. Semenova), in: Second International Congress of CIANS, Abstract, Prague (1975), p. 72.

  9. B. Welch and A. Welch, Anal. Biochem.,30, 161 (1969).

    Google Scholar 

Download references

Authors
  1. N. L. Vekshina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. P. Semenova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vekshina, N.L., Semenova, T.P. Changes in the brain serotonin and noradrenalin level in albino rats during training with emotionally different reinforcement. Bull Exp Biol Med 82, 1600–1602 (1976). https://doi.org/10.1007/BF00790359

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00790359

Key words

Search

Navigation