Advertisement

Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 1, pp 1078–1081 | Cite as

Disturbance of development of the progeny of rats exposed to hydrogen chloride

  • T. E. Pavlova
Experimental Biology
  • 17 Downloads

Abstract

Female Wistar rats were made to inhale hydrogen chloride gas once before pregnancy or on the ninth day of pregnancy. Besides marked disturbances of the state of the lungs, in the experimental rats of both groups changes in renal and hepatic function were observed. The disturbance of the state of the organs in the mother led to developmental changes in the organs of the progeny, manifested as a functional insufficiency of these organs in the postnatal period. A disturbance of of lung (after additional inhalation) and kidney function was found in male progeny of both groups, together with changes in liver function in the male progeny of animals exposed to HCl before pregnancy.

Key Words

Hydrogen chloride lungs kidneys injury to organs of the progeny 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. 1.
    Ya. I. Azhipa, in: Response of the Organism to Small Doses of Ionizing Radiation [in Russian], Moscow (1962), pp. 98–123.Google Scholar
  2. 2.
    S. M. Bekker, Akush. Gin., No. 9, 59 (1968).Google Scholar
  3. 3.
    V. I. Bodyazhina and A. P. Kiryushchenkov, Vopr. Okhr. Mat., No. 12, 3 (1968).Google Scholar
  4. 4.
    O. E. Vyazov, The Immunology of Embryogenesis [in Russian], Moscow (1962).Google Scholar
  5. 5.
    O. E. Vyazov, A. I. Murashova, I. I. Orlova, et al., in: Proceedings of the 10th Scientific Conference on Age Morphology, Physiology, and Biochemistry, [in Russian], Vol. 1, Moscow (1971), pp. 92–93.Google Scholar
  6. 6.
    K. S. Lobyntsev, Yu. I. Savchenkov, and V. P. Tereshchenko, Abstracts of Proceedings of the 9th International Congress of Anatomists [in Russian], Moscow (1970), p. 112.Google Scholar
  7. 7.
    A. I. Murashova, Arkh. Anat., No. 8, 43 (1966).Google Scholar
  8. 8.
    A. I. Murashova, “An Experimental study of humoral connections between homonymous organs of mother and embryo in rats”, Candidate's Dissertation, Moscow (1969).Google Scholar
  9. 9.
    E. I. Novikova and Yu. I. Barashnev, in: New Problems in Pediatrics, [in Russian], No. 5, Sofia (1968), pp. 29–37.Google Scholar
  10. 10.
    L. K. Romanova, Proceedings of a Scientific Conference on Regeneration and Transplantation of Organs and Tissues [in Russian], Gor'kii (1965), pp. 79–85.Google Scholar
  11. 11.
    L. K. Romanova, in: Conditions of Regeneration of Organs in Mammals [in Russian], Moscow (1972), p. p. 149.Google Scholar
  12. 12.
    L. K. Romanova, in: Problems in Establishment of Hygienic Standards During the Study of Late Effects of Exposure to Industrial Substances [in Russian], Moscow (1972), pp. 78–82.Google Scholar
  13. 13.
    I. V. Sanotskii, V. N. Fomenko, G. N. Zaeva, et al., Zh. Vsesoyuz. Khim. Obshch. im. D. I. Mendeleeva,29, No. 2, 146 (1974).Google Scholar
  14. 14.
    N. G. Stepanova, Lab. Delo, No. 5, 49 (1962).Google Scholar
  15. 15.
    M. Ya. Studinikin and G. P. Borisova, Pediatriya, No. 8, 5 (1970).Google Scholar
  16. 16.
    N. I. Shumskaya and N. M. Karamzina, in: The Toxicology of New Industrial Chemicals [in Russian], No. 8, Moscow (1966), pp. 14–27.Google Scholar
  17. 17.
    B. Kauneliené and S. Suksteriené, Sveikatos Apsauga, No. 4, 20 (1974).Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • T. E. Pavlova
    • 1
    • 2
  1. 1.Laboratory of Toxicology, Research Institute of Work Hygiene and Occupational DiseasesAcademy of Medical Sciences of the USSRUSSR
  2. 2.Department of BiologyMoscow Medical Stomatological InstituteUSSR

Personalised recommendations