Bulletin of Experimental Biology and Medicine

, Volume 82, Issue 1, pp 1078–1081 | Cite as

Disturbance of development of the progeny of rats exposed to hydrogen chloride

  • T. E. Pavlova
Experimental Biology


Female Wistar rats were made to inhale hydrogen chloride gas once before pregnancy or on the ninth day of pregnancy. Besides marked disturbances of the state of the lungs, in the experimental rats of both groups changes in renal and hepatic function were observed. The disturbance of the state of the organs in the mother led to developmental changes in the organs of the progeny, manifested as a functional insufficiency of these organs in the postnatal period. A disturbance of of lung (after additional inhalation) and kidney function was found in male progeny of both groups, together with changes in liver function in the male progeny of animals exposed to HCl before pregnancy.

Key Words

Hydrogen chloride lungs kidneys injury to organs of the progeny 


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • T. E. Pavlova
    • 1
    • 2
  1. 1.Laboratory of Toxicology, Research Institute of Work Hygiene and Occupational DiseasesAcademy of Medical Sciences of the USSRUSSR
  2. 2.Department of BiologyMoscow Medical Stomatological InstituteUSSR

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