Abstract
A new modification of the human blood leukocyte migration inhibition test is suggested. The results of clinical trials enable it to be recommended for monitoring the dynamics of cellular immunity and the level of humoral factors in patients with various immunopathological states. By means of the suggested modification and using small amounts of blood, 10 to 15 parallel tests can be carried out simultaneously.
Similar content being viewed by others
Literature Cited
A. G. Artemova and V. I. Ioffe, “The study of cellular immunologic reactivity experimentally in vitro. The phenomenon of specific inhibition of leukocyte migration,” in: Proceedings of the Fourth All-Union Symposium on the Histophysiology of Connective Tissue. Vol. 2. The Cellular Basis of Immunity [in Russian], Nauka, Novosibirsk (1972), pp. 91–94.
G. Bendixen, “Specific inhibition of the in vitro migration of the in vitro migration of leucocytes in ulcerative colitis and Crohn's disease,” Scand. J. Gastroenterol.,2, 214 (1967).
D. Hughes and D. W. Paty, “Macrophage migration inhibition test applied to delaved hypersensitivity in man. I. A mixed lymphocyte reaction between human and guinea pig lymphocytes demonstrated using a sensitive microcapillary,” Z. Immun. Forsch., No. 5, 478 (1972).
Author information
Authors and Affiliations
Additional information
Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 8, pp. 122–124, August, 1975.
Rights and permissions
About this article
Cite this article
Grigor'eva, M.P. Development and clinical trials of a micromodification of the human blood leukocyte migration inhibition test. Bull Exp Biol Med 80, 996–998 (1975). https://doi.org/10.1007/BF00789292
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00789292