Bulletin of Experimental Biology and Medicine

, Volume 80, Issue 2, pp 923–925 | Cite as

Effect of psychotropic drugs on conditioned reflexes in cats after emotional excitation

  • R. M. Salimov


After emotional responses of fear and rage differential inhibition and shortterm memory are disturbed in cats. Trifluoperazine, haloperidol, amitriptyline, imipramine, chlordiazepoxide, diazepam, and benactyzine prevent the development of these disturbances. Chlorpromazine, as well as trifluoperazine and haloperidol in large doses (1 and 2 mg/kg), intensify the disturbances taking place. Unlike neuroleptics, the tranquilizers and antidepressants tested restore normal higher nervous activity over a wider range of doses; consequently, their use is to be preferred for the elimination of adverse sequelae of powerful emotional responses.

Key words

emotional stress conditioned reflex psychotropic drugs 


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • R. M. Salimov
    • 1
  1. 1.Laboratory of Pharmacotherapy of Extremal States, Department of Pharmacology, Institute of PharmacologyAcademy of Medical Sciences of the USSRMoscow

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