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Effect of atp and cocarboxylase on activity of malate dehydrogenase and its isozymes in blood serum and myocardium

  • Biochemistry and Biophysics
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Abstract

Changes in the activity of malate dehydrogenase (MD) and its isozymes in the blood serum and heart muscle of rats were investigated during hypoxia and under the influence of ATP and cocarboxylase. An additional cathodic isozyme (MD4) appeared in the blood serum during hypoxia. Under the influence of ATP and cocarboxylase the metabolic changes in the blood and myocardium induced by hypoxia did not correlate fully.

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Authors and Affiliations

  1. Laboratory of Biochemistry, A. V. Vishnevskii Institute of Surgery, Academy of Medical Sciences of the USSR, Moscow

    I. M. Nosova

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  1. I. M. Nosova
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Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 8, pp. 48–50, August, 1975.

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Nosova, I.M. Effect of atp and cocarboxylase on activity of malate dehydrogenase and its isozymes in blood serum and myocardium. Bull Exp Biol Med 80, 907–909 (1975). https://doi.org/10.1007/BF00789267

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  • DOI: https://doi.org/10.1007/BF00789267

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