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Effect of hypokinesia on structure and mineral content of the long bones in puppies

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The effect of hypokinesia for 2 months on the structure and mineral content of the cortical layer of the humerus, femur, and tibia was investigated in experiments on 6 puppies aged 2 months. The mineral content of the microstructures of the subperiosteal, subendosteal, and intermediate zones of the cortical layer of the long bones of the puppies, investigated by contact microroentgenography, increased under the influence of hypokinesia as a result of predominance of more mature structures resulting from delayed osteogenesis. An increase in the mean diameter of the Haversian canals was found as a result of increased osteoclastic absorption of bone tissue. Resorption also was intensified in the subperiosteal zone, as the result of which this zone and the whole cortical layer became thinner.

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Authors and Affiliations

  1. Department of Pathological Physiology, Moscow Medical Stomatologic Institute. Laboratory of Biophysics, N. N. Priorov Central Institute of Traumatology and Orthopedics, Moscow

    M. N. Pavlova, A. I. Volozhin & I. Sh. Muradov

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  1. M. N. Pavlova
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  2. A. I. Volozhin
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  3. I. Sh. Muradov
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Pavlova, M.N., Volozhin, A.I. & Muradov, I.S. Effect of hypokinesia on structure and mineral content of the long bones in puppies. Bull Exp Biol Med 80, 892–895 (1975). https://doi.org/10.1007/BF00789263

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  • DOI: https://doi.org/10.1007/BF00789263

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