Summary
Complete removal of the left kidney and resection of 1/3 to 1/2 of the right kidney were performed simultaneously in mature rats. The experiment then lasted for 15 months. Regenerative processes continued long after injury, as shown by comparison with the changes observed 3 months and 8 months after operation. The size and weight of the kidney increased. This increase results from enlargement of the renal corpuscles. The lumen of Bowman's capsule becomes smaller, while the thickness of its outer wall increases. The diameter of the convoluted tubules and collecting ducts does not increase, but the thickness of their walls does, causing a reduction in the size of the lumen. The cells in the tubular wall become taller. These restorative processes occur as a result of cellular hyperplasia; and the cells are larger than in control animals.
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Literature Cited
M. A. Vorontsova and L. D. Liozner, Physiological Regeneration (Moscow, 1955) [In Russian].
G. G. Samsonidze, Morphophysical Analysis of Renal Regeneration After Injury (Tbilisi, 1958) [In Russian].
G. G. Samsonidze, Byull. Eksper. Biol. i Med.6, 101 (1959). Original Russian pagination. See C. B. Translation.
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Samsonidze, G.G. Morphological changes in regenerating rat kidney at long intervals after injury. Bull Exp Biol Med 49, 195–197 (1960). https://doi.org/10.1007/BF00788790
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DOI: https://doi.org/10.1007/BF00788790