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The immunogenic properties of explantates of brown-pearce rabbit tumors when cultivated in human serum

  • Microbiology and Immunity
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The explants of a Brown-Pearce rabbit carcinoma cultured on human serum and heterogenic embryonic and yeast extract, show growth in a number of cases, when mixed with fresh undiluted human serum and transplanted intratesticularly in rabbits; later they regress.

Rabbits in which the experimental cultures have regressed twice in the same testis became immune to repeated transplantation of the untreated tumor tissue into the same testis. In these rabbits, antibodies to the tumor and normal rabbit liver are produced more intensively than in the control group.

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Authors and Affiliations

  1. Laboratory of Noninfectious Immunology of the Institute of Experimental Biology, AMN SSSR, Moscow

    M. S. Lomakin

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  1. M. S. Lomakin
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Lomakin, M.S. The immunogenic properties of explantates of brown-pearce rabbit tumors when cultivated in human serum. Bull Exp Biol Med 49, 187–190 (1960). https://doi.org/10.1007/BF00788788

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  • DOI: https://doi.org/10.1007/BF00788788

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