Summary
An insignificant anemia of short duration develops following splenic denervation in dogs. The most characteristic feature of the blood picture in this condition is the presence of fluctuations in the hemoglobin level and especially in that of the red cell count and vitamin B12 concentration, varying from one test to another. It is suggested that splenic denervation tends to disturb the mechanism maintaining a more or less stable level of the mentioned indices within the normal limits.
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Literature Cited
N. N. Beller, The Participation of the Nervous System in the Regulation of the Composition of the Blood and the Oxygen Saturation of the Arterial Blood during Anoxia. Candidate's dissertation (Leningrad, 1957) [In Russian].
V. N. Bukin, L. Ya. Areshkina and L. S. Kutseva, Biokhimiya19, 713 (1954).
R. A. Durinyan, Experimental Analysis of Anemias Caused by the Denervation of Certain Internal Organs. Candidate's dissertation (Moscow, 1956) [In Russian].
M. A. Kalnyn', The Effect of Denervation of the Spleen on the Processes of Hemopoiesis. Author's sunmary of candidate's dissertation (Riga, 1955) [In Russian].
E. L. Kan, Data on the Study of the Influence of the Nervous System on the Composition of the Blood. Candidate's dissertation (Leningrad, 1953) [In Russian].
N. S. Rozanova and E. A. Zhukova, Present Problems of Hematology and Blood Transfusion (Moscow, 1955). 31, p.85 [In Russian].
V. N. Chemigovskii and A. Ya. Yaroshevskii, The Nervous Regulation of the Blood System (Moscow, 1953) [In Russian].
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Markelova, V.F. The effect of denervation of the spleen on the serum vitamin B12 level in dogs. Bull Exp Biol Med 49, 137–140 (1960). https://doi.org/10.1007/BF00788774
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DOI: https://doi.org/10.1007/BF00788774