Bulletin of Experimental Biology and Medicine

, Volume 51, Issue 5, pp 549–554 | Cite as

The importance of prolonged functional stress of the nervous system in the development of lipoidosis in the aorta and myocardial lesions in rabbits

  • P. S. Khomulo
Pathological Physiology and General Pathology


Lipoidosis of aorta with a thickening of the tunica intima of the coronary vessels and dystrophy of the cardiac muscle was seen to develop in prolonged functional stress of the nervous system (12–23 months) in rabbits which received food with or without cholesterol.

Lipoid deposition into the wall of aorta occurred with the cholesterol blood level equal to 35–70 mg%; however, the content of free cholesterol, β-lipoproteids, and neutral fats was found to be increased in the blood of experimental rabbits. The mentioned lesions in the aorta, the coronary vessels of the heart, and the cardiac muscle are the sequence of prolonged functional stress of the nervous system.


Public Health Cholesterol Nervous System Blood Level Cardiac Muscle 
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Copyright information

© Consultants Bureau Enterprises, Inc. 1961

Authors and Affiliations

  • P. S. Khomulo
    • 1
  1. 1.Department of Pathological PhysiologyLeningrad Pediatric Medical SchoolLeningradUSSR

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