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The effect of ribonucleic acid and its hydrolyzates on the uptake of glycine-1-C14 by proteins of normal and tumor tissues

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Ribonucleic acid and its hydrolyzates exert a stimulating effect on the incorporation of glycine-1-C14 into the proteins of minced normal organs (pancreas, liver, kidneys, spleen, brain, and thymus) of rats and have almost no effect on the incorporation of glycine radioactivity into the proteins of minced sarcoma M-1 and transplanted cholangioma at late stages of its growth. At early stages of cholangioma growth some stimulation of radioactivity incorporation is noted. The effect of the stimulation is independent of the length of RNA hydrolysis.

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Authors and Affiliations

  1. Biochemical Laboratory of the P. A. Gertsen State Oncological Institute, Moscow

    I. B. Zbarskii & N. P. Karuzina

Authors
  1. I. B. Zbarskii
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  2. N. P. Karuzina
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Zbarskii, I.B., Karuzina, N.P. The effect of ribonucleic acid and its hydrolyzates on the uptake of glycine-1-C14 by proteins of normal and tumor tissues. Bull Exp Biol Med 48, 1375–1379 (1959). https://doi.org/10.1007/BF00788351

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  • DOI: https://doi.org/10.1007/BF00788351

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