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Relation of splenic activity to that of other organs

Communication III. Effect of diathermy applied to spleen and of spleen extracts on the liver and hemopoietic organs during pathological conditions

  • Pathological Physiology and General Pathology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Studies were made of the glycemic reaction to adrenalin, the protein content and protein fractions in the blood serum, the glycogen and fat contents of the liver, and the ability of the liver to take up sulfur-labeled methionine, to bind phenols, and to oxidize tyrosine. It was shown that diathermy applied to the spleen improves the condition of the liver in rabbits and white rats with hepatitis induced by carbon tetrachloride.

An analogous effect was achieved by an extract from an hyperactive spleen obtained by cutaneous-muscular union of pairs of animals as parabionts.

In a further set of experiments it was shown that splenic diathermy and extracts from a hyperactive spleen cause a marked improvement in peripheral blood and bone marrow indices in rabbits suffering from benzene poisoning or irradiation sickness.

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Geller, L.I. Relation of splenic activity to that of other organs. Bull Exp Biol Med 48, 1358–1364 (1959). https://doi.org/10.1007/BF00788347

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  • DOI: https://doi.org/10.1007/BF00788347

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