The formation of immune antibodies in rabbits during the growth of a brown-pearce tumor
- 13 Downloads
Experiments were conducted on healthy rabbits and on those suffering from cancer. The author undertook a comparative study of the antibody production resulting from administration of heterologous antigen (water-salt extract of the ascitic cells of the Ehrlich adenocarcinoma), and of homologous antigen (water-salt extract of the Brown-Pearce tumor). In immunization with a heterologous tumor antigen immunogenesis was depressed in the affected animals in comparison with the control ones. As to immunization with a homologous tumor antigen, it caused no antibody formation either in the experimental or in the control group of animals.
KeywordsPublic Health Adenocarcinoma Tumor Antigen Antibody Production Antibody Formation
Unable to display preview. Download preview PDF.
- A. A. Bogomolets, General and Special Oncology, vol. 1, pp. 389–392, Moscow-Leningrad, 1940 [In Russian].Google Scholar
- I. Kirichinskaya, M. Sirotina, Med. Zhur. Ukrain., 20, 2, 71–76 (1950).Google Scholar
- M. S. Lomakin, Byull. Éksptl. Biol. i Med., 46, No. 9, 92–96 (1958). Original Russian pagination. See C.B. Translation.Google Scholar
- D. L. Larson and L. Tomlinson, J. Clin. Invest., 1953, v. 32, p. 317–321.Google Scholar
- S. Leskowitz, L. Phillipino, G. Hendrick et al., Cancer, 1957, v. 10, p. 1103–1105.Google Scholar
- J. Logan, New Zealand, M. J., 1953, v. 52, p. 400–402.Google Scholar
- I. A. Parfent'ev, E. E. Cliffton and F. Duran-Reynals, Science, 1951, v. 113, p. 523–524.Google Scholar
- C. M. Southam, V. Goldsmith and J. H. Burchenal, Cancer, 1951, v. 4, p. 1031–1042.Google Scholar