Bulletin of Experimental Biology and Medicine

, Volume 46, Issue 4, pp 1225–1227 | Cite as

The influence of congo red on the effects of ditiline

  • P. E. Diablova
Pharmacology
  • 15 Downloads

Summary

In low concentrations (1·10−6) congo red intensifies the contractions of the isolated m. rectus abdominis produced by ditiline. Higher concentrations (1·10−4) of congo red depress these contractions. The first effect is probably connected with the depression of cholinesterase, and the second — with the action of the dye on the muscle. The formation of a congo red compound with the quaternary ammonium bases — ditiline (dicholine ester of succinic acid) and curarine (contained in curare), as suggested in pertinent literature, could not be established by means of a spectrographic analysis.

Keywords

Public Health Spectrographic Analysis Ammonium Ester Cholinesterase 

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Copyright information

© Consultants Bureau 1959

Authors and Affiliations

  • P. E. Diablova
    • 1
  1. 1.Department of Pharmacology of the Leningrad State Institute of Pediatric MedicineLeningradUSSR

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