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Bulletin of Experimental Biology and Medicine

, Volume 46, Issue 4, pp 1225–1227 | Cite as

The influence of congo red on the effects of ditiline

  • P. E. Diablova
Pharmacology

Summary

In low concentrations (1·10−6) congo red intensifies the contractions of the isolated m. rectus abdominis produced by ditiline. Higher concentrations (1·10−4) of congo red depress these contractions. The first effect is probably connected with the depression of cholinesterase, and the second — with the action of the dye on the muscle. The formation of a congo red compound with the quaternary ammonium bases — ditiline (dicholine ester of succinic acid) and curarine (contained in curare), as suggested in pertinent literature, could not be established by means of a spectrographic analysis.

Keywords

Public Health Spectrographic Analysis Ammonium Ester Cholinesterase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature Cited

  1. [1]
    V. M. Karasik, A. M. Petrun'kina and L. M. Petrun'kin, Biochem. Ztschr. 1929, Bd. 210, S. 70–75.Google Scholar
  2. [2]
    V. M. Karasik, M. M. Likhachev, Biull. Vsesoiuzn. inst. Eksper. Med. 5, 47–49 (1934).Google Scholar
  3. [3]
    I. R. Petrov, Arch. exper. Patho. u. Pharmakol., 1924, Bd. 103, S. 196–208; 1925, Bd. 106, S. 214–222; Arkh. Biol. Nauk, 31, 1, 59–68 (1931).Google Scholar
  4. [4]
    R. S. Rybolovlev. Farmakol. l Toksikolol. No. 6, 30–38 (1952).Google Scholar
  5. [5]
    F. Brücke, W. Kobinger and O. Kraupp, Arch. exper. Pathol. u. Pharmakol. 1955, Bd. 224, S. 123–136.Google Scholar
  6. [6]
    C. J. Kensler, J. Pharmacol. a. Exper. Therap. 1949, v. 95, p. 28–44.Google Scholar

Copyright information

© Consultants Bureau 1959

Authors and Affiliations

  • P. E. Diablova
    • 1
  1. 1.Department of Pharmacology of the Leningrad State Institute of Pediatric MedicineLeningradUSSR

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