The influence of congo red on the effects of ditiline
In low concentrations (1·10−6) congo red intensifies the contractions of the isolated m. rectus abdominis produced by ditiline. Higher concentrations (1·10−4) of congo red depress these contractions. The first effect is probably connected with the depression of cholinesterase, and the second — with the action of the dye on the muscle. The formation of a congo red compound with the quaternary ammonium bases — ditiline (dicholine ester of succinic acid) and curarine (contained in curare), as suggested in pertinent literature, could not be established by means of a spectrographic analysis.
KeywordsPublic Health Spectrographic Analysis Ammonium Ester Cholinesterase
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- V. M. Karasik, A. M. Petrun'kina and L. M. Petrun'kin, Biochem. Ztschr. 1929, Bd. 210, S. 70–75.Google Scholar
- V. M. Karasik, M. M. Likhachev, Biull. Vsesoiuzn. inst. Eksper. Med. 5, 47–49 (1934).Google Scholar
- I. R. Petrov, Arch. exper. Patho. u. Pharmakol., 1924, Bd. 103, S. 196–208; 1925, Bd. 106, S. 214–222; Arkh. Biol. Nauk, 31, 1, 59–68 (1931).Google Scholar
- R. S. Rybolovlev. Farmakol. l Toksikolol. No. 6, 30–38 (1952).Google Scholar
- F. Brücke, W. Kobinger and O. Kraupp, Arch. exper. Pathol. u. Pharmakol. 1955, Bd. 224, S. 123–136.Google Scholar
- C. J. Kensler, J. Pharmacol. a. Exper. Therap. 1949, v. 95, p. 28–44.Google Scholar