Advertisement

Bulletin of Experimental Biology and Medicine

, Volume 46, Issue 3, pp 1137–1142 | Cite as

Activation of the division and growth of cells during regeneration

  • I. A. Alov
  • N. F. Semenova
Experimental Biology

Summary

An increase of mitotic activity, the size of the cells and their nuclei and the increase of content of RNA and DNA was noted in regeneration of salivary glands in mice. Analogous changes were noted in uninjured gland on the contralateral side. Administration of an extract of salivary gland caused the rise of mitotic activity, an increased content of nucleic acids in the cells and hypertrophy of the cells. Injection of liver extract into the check's embryo brought about an increase of the relative weight of the liver, the rise of mitotic activity and cellular hypertrophy. A conclusion was drawn that protein and the products of its disintegration possesses an organospecific effect on the growth and mitosis of cells.

Keywords

Public Health Nucleic Acid Salivary Gland Relative Weight Mitotic Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature Cited

  1. [1]
    I. A. Alov, Doklady Akad. Nauk SSSR 104, 5, 783 (1955).Google Scholar
  2. [2]
    Idem 111, 1, 190–192 (1956).Google Scholar
  3. [3]
    I. A. Alov and A. A. Zhirnova, Ibid., 114, 1, 192–194 (1957).Google Scholar
  4. [4]
    J. Brachet, The Nucleic Acids Original Russian pagination. See C.B. Translation. p. 320, Moscow (1957).Google Scholar
  5. [5]
    L. M. Ermolenko, Biull. Eksptl. Biol. i Med. 12, 102–107 (1957). Original Russian pagination. See C.B. Translation.Google Scholar
  6. [6]
    B. V. Kedrovskii, Uspekhi Sovremennoi Biol. 15, 3, 295–309 (1942).Google Scholar
  7. [7]
    G. D. Tumanishvili, K. M. Dzhandieri and I. K. Svanidze, Doklady Akad. Nauk SSSR 106, 6, 1107–1109 (1956).Google Scholar
  8. [8]
    J. Brachet, Arch. biol. Liege v. 53, p. 207 (1941).Google Scholar
  9. [9]
    T. Caspersson, Naturwissenschaften Bd. 28, S. 33–43 (1941).Google Scholar
  10. [10]
    J. Davidson, Cold Spring Harb. Symp., v. 12, p. 50 (1947).Google Scholar
  11. [11]
    J. L. Ebert, Proc. Nat. Acad. Sc., USA, v. 40, p. 337 (1954).Google Scholar
  12. [12]
    J. C. Fardon, Winger et al., Proc. Soc. Exper. Biol. a Med. v. 72, pp. 568–569 (1949).Google Scholar
  13. [13]
    H. Teir, Acta Path. et microbiol. Scand. v. 30, pp. 158–183 (1952).Google Scholar
  14. [14]
    H. Teir and A. Kilunen, Ibid v. 30, pp. 184–193 (1952).Google Scholar
  15. [15]
    P. B. Weisz, J. Exper. Zool. v. 131, pp. 137–162 (1956).Google Scholar

Copyright information

© Consultants Bureau, Inc. 1959

Authors and Affiliations

  • I. A. Alov
    • 1
  • N. F. Semenova
    • 1
  1. 1.Department of Histology of the Khabarovsk Medical InstituteKhabarovskUSSR

Personalised recommendations