Bulletin of Experimental Biology and Medicine

, Volume 46, Issue 3, pp 1137–1142 | Cite as

Activation of the division and growth of cells during regeneration

  • I. A. Alov
  • N. F. Semenova
Experimental Biology


An increase of mitotic activity, the size of the cells and their nuclei and the increase of content of RNA and DNA was noted in regeneration of salivary glands in mice. Analogous changes were noted in uninjured gland on the contralateral side. Administration of an extract of salivary gland caused the rise of mitotic activity, an increased content of nucleic acids in the cells and hypertrophy of the cells. Injection of liver extract into the check's embryo brought about an increase of the relative weight of the liver, the rise of mitotic activity and cellular hypertrophy. A conclusion was drawn that protein and the products of its disintegration possesses an organospecific effect on the growth and mitosis of cells.


Public Health Nucleic Acid Salivary Gland Relative Weight Mitotic Activity 
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Copyright information

© Consultants Bureau, Inc. 1959

Authors and Affiliations

  • I. A. Alov
    • 1
  • N. F. Semenova
    • 1
  1. 1.Department of Histology of the Khabarovsk Medical InstituteKhabarovskUSSR

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