Bulletin of Experimental Biology and Medicine

, Volume 46, Issue 3, pp 1116–1120 | Cite as

The relationship between the titer of tumor antibodies and the character of the antigenic stimulus

  • M. S. Lomakin
Microbiology and Immunity


Serums with a comparatively high titer of immune antibodies were obtained in immunization of rabbits by ascitic cells of malignant tumors (Ehrlich's adenocarcinoma of mice and Iosida's sarcoma of rats). Serums with lower titers of immune antibodies were recovered in immunization of rabbits by the water-salt extracts of the tissue of subcutaneous forms of tumors. Serums of the first, as well as of the second type are not very specific: they react in comparatively high titers with the antigens from the tumor tissues and with those from the tissues of normal organs of the laboratory animals.


Public Health Adenocarcinoma Sarcoma Tumor Tissue Malignant Tumor 
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Literature Cited

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Copyright information

© Consultants Bureau, Inc. 1959

Authors and Affiliations

  • M. S. Lomakin
    • 1
  1. 1.Laboratory of Noninfectious Immunology of the Institute of Experimental BiologyAMN SSSRMoscow

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