Summary
Forty experiments were carried out on dogs with the employment of oxygen therapy during the period of recovery from clinical death caused by acute hemorrhage. Oxygen therapy was carried out by 3 methods commonly used in the clinic: by an apparatus for artificial circulation, by inhalation of oxygen from a pillow or in an oxygen tent after rehabilitation of spontaneous respiration. The efficacy of oxygen therapy was judged by the general condition of animals, the span of life after the clinical death and by the morphological changes in the brain and internal organs.
The animals which are in condition of hypoxia after clinical death possess an increased sensitivity to oxygen and hyperoxia may easily occur, causing their death. Artificial respiration with 100% oxygen in resuscitation during clinical death is not expedient. During the recovery period after clinical death strict dosimetry of oxygen therapy should be observed. Certain favorable effects are obtained only when resuscitation is carried out for 4 hours in a tent with oxygen content of 40–50% in 80–112 minutes after commencing the resucitation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
N. V. Angstvurm, Oxygen Therapy and Oxygen Deficiency, In Russian. Kiev, pp. 195–198 (1952).
E. M. Berkovich and L. G. Okhnianskaia, Occupational Disease Clinic, In Russian. Moscow, pp. 63–78 (1952).
O. N. Bulanova, Conference on The Problem of Compensatory Accommodations. Reports of Proceedings, In Russian. Moscow, pp. 12–13 (1958).
Kh. I. Vainshtein, Oxygen Therapy and Oxygen Deficiency, In Russian. Kiev, pp. 171–177 (1952).
M. S. Gaevskaia, Arkh. Pat. 8, 1–2, pp. 4–12 (1946).
Z. S. Gershenovich and L. A. Krichevskaia, Ukr. Biokh. Zhur. 22, 3, pp. 336–343 (1950).
A. G. Dembo, Deficiency of the Function of External Respiration, In Russian. Leningrad (1957).
S. M. Dionesov, B. D. Kravshinski and S. I. Prikladovitski, Fiziol. Zhur. SSSR, 17, 5, pp. 1004–1017 (1934).
G. N. Zilov, Biull. Eksptl. Biol. i Med. No. 12, pp. 22–25 (1953).
V. A. Negovskii, Hypoxia, In Russian. Kiev, pp. 63–67 (1949).
F. Ia. Primak, Oxygen Therapy and Oxygen Deficiency, In Russian. Kiev, pp. 267–275 (1952).
N. P. Romanova, Zhur. Nevropatol. i Psikhiatr. 56, 1, pp. 49–55 (1956).
I. A. Sapov, The Role of the Nervous System in the Mechanism of the Effect of Oxygen, Author's Abstract of Candidate's Dissertation, In Russian. Leningrad (1952).
N. N. Sirotinin, Oxygen Therapy and Oxygen Deficiency, In Russian. Kiev, pp. 148–163 (1952).
E. M. Smirenskaia, Arkh. Pat. No. 1#x2013;2, pp. 12–21 (1946).
E. M. Smirenskaia and E. S. Zolotokrylina, Arkh. Pat. No. 1, pp. 99–100 (1956).
S. N. Sorinson and L. N. Postnikova, Oxygen Therapy and Oxygen Deficiency, In Russian. Kiev, pp. 198–207 (1952).
W. M. Boothly, C. W. Mayo and W. R. Lovelace, J. A. M. A. v. 113, pp. 477–482 (1939).
P. Bert, La pression barometrique Recherches de physiologie experimental, Paris (1878).
J. H. Comroe, R. D. Dripps, P. R. Dumke and M. Deming, J. A. M. A. v. 128, pp. 710–718 (1945).
J. H. Comroe, E. R. Bahnson and E. O. Coates, J. A. M. A. v. 143, pp. 1044–1048 (1950).
Ewans, Quoted by Comroe and Dripps
R. Grandpiere and C. Franck, J. Aviat. Med. v. 23, pp. 181–185 (1952).
R. Grandpiere, C. Franck and R. Lemaire, Compt. rend. Soc. Biol. v. 142, pp. 1028–1029 (1948).
R. Grandpiere, C. Franck and R. Lemaire, J. Physiol. v. 42, pp. 5–31 (1950).
H. L. Motley, Bull. New York Acad. Med. v. 26, pp. 479–492 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Smirenskaia, E.M., Romanova, N.P. Oxygen therapy in the recovery period following clinical death. Bull Exp Biol Med 46, 1090–1095 (1958). https://doi.org/10.1007/BF00787941
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00787941