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The role of the adrenals in the restoration of the vital functions after clinical death

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The restoration of vital functions (Professor V. A. Negovskii's method) was studied following lethal desanguination in adrenalectomized cats.

Several groups of animals were experimented upon: observation of the first group of animals was conducted 16–17 hours after adrenalectomy, adrenalectomy with administration of saline solution and cortisone (30 mg/kg of body weight per course), on the third —4 days after adrenalectomy with administration of saline solution and large doses of cortisone (70 mg/kg of body weight per course).

The restoration of vital functions was best in adrenalectomized animals which received large doses of cortisone. The authors believe that cortisone is of value in the therapy of terminal conditions.

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Literature Cited

  1. A. A. Bogomolets, Collected Works, 1, 13–164, Kiev, 1956. In Russian.

    Google Scholar 

  2. M. Gaevskaya-Sokolova, The Carbohydrate Metabolism of the Cerebral Cortex During Extinction and Restoration of the Vital Functions of the Body. Author's abstract of Dissertation for Doctorate, Moscow, 1955.

  3. A. G. Ginetsinskii and A. V. Lebedinskii, A Course in Normal Physiology, Moscow, 1956. In Russian

  4. P. D. Gorizontov, Patol. Fiziol. i Éksptl. Terap. 1, 4, 3–10 (1957).

    Google Scholar 

  5. M. G. Kolpakov, First Plenum of the Siberian Society of Pathophysiologists, 66–67, Tomsk, 1957. In Russian

  6. Yu. M. Levin, First Plenum of the Siberian Society of Pathophysiologists, 71–72, Tomsk, 1957. In Russian

  7. G. L. Lyuban, Transactions of a Conference on the Pathophysiology and Therapy of Terminal States, p. 166, Moscow, 1954; Byull. Éksptl. Biol. i Med. No. 7, 19–22 (1956). In Russian. Original Russian pagination. See C. B. Translation.

  8. N. B. Medvedeva, Experimental Endocrinology, Kiev, 1946. In Russian.

  9. V. A. Negovskii, The Pathophysiology and Therapy of Agony and Clinical Death, Moscow, 1954. In Russian.

  10. I. R. Petrov, Oxygen Starvation of the Brain, Leningrad, 1949. In Russian.

  11. V. S. Shapot, Uspekhi Sovremennoi Biol. 34, 2, 244–267 (1952).

    Google Scholar 

  12. G. S. Yakobson, First Plenum of the Siberian Society of Pathophysiologists, 69–70, Tomsk, 1957. In Russian.

  13. A. Gerhards, Chirug, 28, 7 (1957).

  14. F. Lagrot and G. Antonie, Mem. Acad. Chir., 83, 17–18 (1957).

    Google Scholar 

  15. H. J. Selye, Clin. Endocrinol. 6, 117–230 (1946).

    Google Scholar 

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Authors and Affiliations

  1. Department of Pathological Physiology, Novosibirsk Medical Institute, Novosibirsk, USSR

    M. G. Kolpakov, M. G. Polyak & G. S. Yakobson

Authors
  1. M. G. Kolpakov
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  2. M. G. Polyak
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  3. G. S. Yakobson
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Kolpakov, M.G., Polyak, M.G. & Yakobson, G.S. The role of the adrenals in the restoration of the vital functions after clinical death. Bull Exp Biol Med 47, 282–288 (1959). https://doi.org/10.1007/BF00787774

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  • DOI: https://doi.org/10.1007/BF00787774

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