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Formation of an ion depot in the skin by electrophoresis

  • Pharmacology
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Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Experiments were staged on dogs. As established, sulfanilamide preparations and antibiotics (penicillin, streptomycine, biomycine, teramycine, and tetramycine), administered by electrophoresis method, were not simultaneously eliminated from different tissues.

High concentration of the preparations studied persisted in the skin under an active electrode for longer periods of time, forming a “skin ion depot”.

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Literature Cited

  1. I. A. Abrikosov, Collection: Physiotherapy [in Russian] (Moscow, 1955), p. 33.

  2. L. I. Grebenik, Collection: Methods of Experimental Chemotherapy [in Russian] (Moscow, 1959), p. 431.

  3. Ya. S. Perlin, Galvano- and Galvano-Ionic Therapy [in Russian] (Moscow, 1958).

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  5. L. R. Rubin, Physical Methods of Investigation and Treatment in Stomatology [in Russian] (Moscow, 1955), p. 126.

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Barsukov, N.A. Formation of an ion depot in the skin by electrophoresis. Bull Exp Biol Med 54, 872–874 (1963). https://doi.org/10.1007/BF00787641

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  • DOI: https://doi.org/10.1007/BF00787641

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