Summary
The ACTH content of the hypophysis of rats rises from a minimum in the morning to a maximum in the evening hours. These fluctuations are associated with the diurnal rhythm of light and darkness, and are abolished under conditions of continual light or darkness for 30 days. Rhythmic fluctuations of the ascorbic acid content of the adrenals are also found, with maximum values in the evening, and these are likewise abolished by maintenance under conditions of constant illumination.
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Eskin, I.A., Mikhailova, N.V. Photoperiodicity and the function of the hypophysis and the adrenal cortex. Bull Exp Biol Med 46, 999–1002 (1958). https://doi.org/10.1007/BF00787344
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DOI: https://doi.org/10.1007/BF00787344